Radiography
Volume 15, Issue 4 , Pages 283-291 , November 2009

A survey of techniques to reduce and manage external beam radiation-induced xerostomia in British oncology and radiotherapy departments

  • Andrew Macknelly

      Affiliations

    • Norfolk and Norwich University Hospital, United Kingdom
  • ,
  • Jane Day

      Affiliations

    • Faculty of Health, Wellbeing and Science, University Campus Suffolk, Waterfront Building, Neptune Quay, Ipswich, United Kingdom
    • Corresponding Author InformationCorresponding author. Tel.: +44 1473 338646.

Received 22 August 2008 ,Revised 21 December 2008 ,Accepted 26 January 2009.

References 

  1. In:  Hanks P editors. Collins english dictionary. London: Collins; 1985;
  2. Anand A, Jain J, Negi P, Chaudhoory A, Sinha S, Choudhury P, et al. Can dose reduction to one parotid gland prevent xerostomia? – A feasibility study for locally advanced head and neck cancer patients treated with intensity-modulated radiotherapy. Clinical Oncology. 2006;18(6):497–504
  3. Berk L, Shivnani A, Small W. Pathophysiology and management of radiation-induced xerostomia. Journal of Supportive Oncology. 2005;3(3):191–200
  4. Wells M. Oropharyngeal effects of radiotherapy. In:  Faithfull S,  Wells M editor. Supportive care in radiotherapy. Edinburgh: Churchill Livingstone; 2003;
  5. Patt R, Lang S. The complete guide to relieving cancer pain and suffering. Oxford: Oxford University Press; 2004;
  6. Joint Formulary Committee . British national formulary 51. London: British Medical Association and Royal Pharmaceutical Society of Great Britain; 2006;
  7. Braam P, Terhaard C, Roesnink J, Cornelis P, Raaijmakers C. Intensity-modulated radiotherapy significantly reduces xerostomia compared with conventional radiotherapy. International Journal of Radiation Oncology, Biology and Physics. 2006;
  8. Wendt TG, Abbasi-Senger N, Salz H, Pinquart I, Koscelny S, Przetak S, et al. 3D-conformal-intensity modulated radiotherapy with compensators for head and neck cancer: clinical results of normal tissue sparing. Radiation Oncology. 2006;1:18;Available from: http://www.ro-journal.com/content/1/1/18[accessed on 21.11.06]
  9. Ng M, Porceddu S, Milner A, Corry J, Hornby C, Hope G, et al. Parotid-sparing radiotherapy: does it really reduce xerostomia?. Clinical Oncology. 2005;17(8):610–617
  10. Eisbruch A, Ten Haken R, Kim H, Marsh L, Ship J. Dose, volume, and function relationships in parotid salivary glands following conformal and intensity modulated irradiation of head and neck cancer. International Journal of Radiation Oncology, Biology and Physics. 1999;45(3):577–587
  11. British Columbia Cancer Agency. Amifostine. 2006. Available from: http://www.bccancer.bc.ca/HPI/DrugDatabase/DrugIndexPro/amifostine.htm [accessed 20.02.07].
  12. Brizel D, Wasserman T, Henke M, Strnad V, Rudat V, Monnier A, et al. Phase III randomized trial of amifostine as a radioprotector in head and neck cancer. Journal of Clinical Oncology. 2000;18(19):3339–3345
  13. Antonadou D, Pepelassi M, Synodinou M, Puglisi M, Throuvalas N. Prophylactic use of amifostine to prevent radiochemotherapy-induced mucositis and xerostomia in head and neck cancer. International Journal of Radiation Oncology, Biology and Physics. 2002;52(3):739–747
  14. Hodson D, Browman G, Thephamongkhol K, Oliver T, Zuraw L. The role of amifostine as a radioprotectant in the management of patients with squamous cell head and neck cancer. 2004. Available from: http://www.cancercare.on.ca/pdf/pebc5-8f.pdf [accessed 20.02.07].
  15. Koukourakis M, Danielidis V. Preventing radiation-induced xerostomia. Cancer Treatment Reviews. 2005;31(7):546–554
  16. Gosselin T, Raj K, Clough R, Brizel D. Amifostine for xerostomia – normal tissue protection at what cost?. International Journal of Radiation Oncology, Biology and Physics (Supplement). 2005;63(2):S128
  17. Lindegaard C, Grau C. Has the outlook improved for amifostine as a clinical radioprotector?. Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology. 2000;57(2):113–118
  18. Lu W. Acupuncture for side effects of chemoradiation therapy in cancer patients. Seminars in Oncology Nursing. 2005;21(3):190–195
  19. Jedel E. Acupuncture in xerostomia, a systematic review. Journal of Oral Rehabilitation. 2005;32(6):392–396
  20. The Columbia electronic encyclopaedia. 2005. Available from: http://columbia.thefreedictionary.com/pilocarpine [accessed 20.02.07].
  21. Haddad P, Karimi M. A randomised, double-blind, placebo-controlled trial of concomitant pilocarpine with head and neck irradiation for prevention of radiation-induced xerostomia. Radiotherapy and Oncology. 2002;64(1):29–32
  22. Bartels C. Helping patients with dry mouth. 2007. Available from: http://www.oralcancerfoundation.org/dental/xerostomia.htm [accessed 02.02.07].
  23. Society and College of Radiographers . Contact details for departments of radiotherapy and clinical oncology in the United Kingdom. London.: College of Radiographers; 2006;
  24. Parahoo K. Nursing research, principles, process and issues. 2nd ed.. Basingstoke: Palgrave Macmillan; 2006;
  25. National Institute for Clinical Health and Excellence (NICE) . Improving outcomes in head and neck cancers: the manual. London: Office of Public Sector Information; 2004;
  26. Bomford C, Kunkler I. Walter and Miller's textbook of radiotherapy. 6th ed.. Edinburgh: Churchill Livingstone; 2003;
  27. Cancer Research UK. 2006. Available from: http://www.cancerhelp.org.uk/help/default.asp?page=10427 [accessed 02.02.07].
  28. Department of Health . The NHS cancer plan, a plan for investment, a plan for reform. London: Department of Health; 2000;
  29. The Institute of Cancer Research. PARSPORT. 2006. Available from: http://www.icr.ac.uk/research/research_sections/clinical_trials/clinical_trials_list/2380_disease.shtml [accessed 23.12.06].
  30. Bourn J. The NHS cancer plan: a progress report. London: National Audit Office; 2005;

PII: S1078-8174(09)00003-0

doi: 10.1016/j.radi.2009.01.002

Radiography
Volume 15, Issue 4 , Pages 283-291 , November 2009