Radiography
Volume 15, Issue 3 , Pages 258-261, August 2009

End-systolic stress–velocity relation and circumferential fiber velocity shortening for analysing left ventricular function in mice

  • A. Fayssoil

      Affiliations

    • Cardiologie, Hôpital européen Georges Pompidou, 20, rue le blanc, Paris, France
    • Corresponding Author InformationCorresponding author. Tel.: +33 667855792.
  • ,
  • G. Renault

      Affiliations

    • CNRS UMR 8104, Inserm, U567, Institut Cochin, Université Paris Descartes, Paris, France
  • ,
  • F. Fougerousse

      Affiliations

    • Genethon, RD, Evry, France

Received 28 February 2008; received in revised form 2 October 2008; accepted 14 October 2008.

Abstract 

Traditionally, analysing left ventricular (LV) performance relies on echocardiography by evaluating shortening fraction (SF) in mice. SF is influenced by load conditions. End-systolic stress–velocity (ESSV) relation and circumferential fiber velocity (VcF) shortening are more relevant parameters for evaluating systolic function regardless load conditions particularly in mice's models of heart failure.

Keywords: Systolic wall stress, Circumferential fiber velocity

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PII: S1078-8174(08)00103-X

doi:10.1016/j.radi.2008.10.002

Radiography
Volume 15, Issue 3 , Pages 258-261, August 2009