Radiography
Volume 12, Issue 2 , Pages 96-104 , May 2006

Can high frequency ultrasound predict metastatic lymph nodes in patients with invasive breast cancer?

  • Gillian R. Clough

      Affiliations

    • University of Bradford, Unity Building, 25 Trinity Road, Bradford BD5 0BB, UK
    • Corresponding Author InformationCorresponding author. Tel.: +44 1274 236237; fax: +44 1484 716380.
  • ,
  • John Truscott

      Affiliations

    • University of Leeds, UK
  • ,
  • Isobel Haigh

      Affiliations

    • Leeds Teaching Hospitals NHS Trust, UK

Received 4 May 2004 ,Accepted 1 April 2005.

References 

  1. Quinn M, Allen E. Changes in incidence of mortality from breast cancer in England and Wales since the introduction of screening. BMJ. 1995;311:1391–1395
  2. Blanks RG, Moss SM, McGahan CE, Quinn MJ, Babb PJ. Effect of NHS breast screening programme on mortality from breast cancer in England and Wales, 1990–8: comparison of observed with predicted mortality. BMJ. 2000;321:665–669
  3. National Statistics . Death registrations 2000: cause, England and Wales. Health Stat Q. 2001;10:60–66
  4. Harries SA, Lawrence RN, Scrivener R, Fieldman NR, Kissin MW. A survey of the management of breast cancer in England and Wales. Ann R Coll Surg Engl. 1996;78:197–202
  5. Chetty U, Jack W, Prescott RJ, Tyler C, Rodger A. Management of the axilla in operable breast cancer treated by breast conservation: a randomised clinical trial. Br J Surg. 2000;87:163–169
  6. Cabanes PA, Salmon RJ, Vilcoq JR, Durand JC, Fourquet A, Gautier C, et al. Value of axillary dissection in addition to lumpectomy and radiotherapy in early breast cancer. Lancet. 1992;339:1245–1248
  7. Elston CW, Ellis IO. Pathological prognostic factors in breast cancer. The value of histological grade in breast cancer: experience from a large study with long-term follow-up. Histopathology. 1991;19:403–410
  8. Meek AG. Breast radiotherapy and lymphoedema. Cancer. 1998;83(Suppl. 12):2788–2802
  9. Mansel R. Axillary lymphatic mapping against nodal axillary clearance (ALMANAC) protocol: a randomised trial of sentinel node guided axillary therapy compared with standard axillary therapy in early breast cancer. Medical research council –Wales office of research & development in health and social care; 1999;
  10. Morris PJ, Wood WC. 2nd ed.. Oxford textbook of surgery. vol. 2. Oxford: University Press; 2000;
  11. Ranaboldo CJ, Mitchel A, Royle GT, Theaker GM, Taylor I. Axillary nodal status in women with screen-detected breast cancer. Eur J Surg Oncol. 1993;19:130–133
  12. Walls J, Boggis CR, Wilson M, Asbury DL, Roberts JV, Bundred NJ, et al. Treatment of the axilla in patients with screen-detected breast cancer. Br J Surg. 1993;80:436–438
  13. Rubaltelli L, Proto E, Salmaso R, Bartoletto P, Candiani F, Cagol P. Sonography of abnormal lymph nodes in vitro: correlation of sonographic and histologic findings. AJR Am J Roentgenol. 1990;155:1241–1244
  14. Vassallo P, Edel G, Roos N, Naguib A, Peters PE. In-vitro high-resolution ultrasonography of benign and malignant lymph nodes. A sonographic-pathologic correlation. Invest Radiol. 1993;28(8):698–705
  15. Feu J, Tresserra F, Fabregas R, Navarro B, Grases PJ, Suris JC, et al. Metastatic breast carcinoma in axillary lymph nodes: in vitro US detection. Radiology. 1997;205:831–835
  16. Tateishi T, Machi J, Feleppa EJ, Oishi R, Furumoto N, McCarthy LJ, et al. In vitro B-mode ultrasound criteria for diagnosing axillary lymph node metastasis of breast cancer. J Ultrasound Med. 1999;349–356
  17. Glynne-Jones R, Makepeace AR, Spittle MF, Lees WR. A possible role for ultrasound of the axilla in staging primary breast cancer. Clin Oncol. 1990;2:35–38
  18. Vassallo P, Wernecke K, Roos N, Peters PE. Differentiation of benign from malignant superficial lymphadenopathy: the role of high resolution US. Radiology. 1992;183:215–220
  19. Bruneton JN, Balu-Maestro C, Marcy PY, Melia P, Mourou MY. Very high frequency (13 MHz) ultrasonographic examination of the normal neck: detection of normal lymph nodes and thyroid nodules. J Ultrasound Med. 1994;13:87–90
  20. Yang WT, Ahuja A, Tang A, Suen M, King W, Metreweli C. Ultrasonographic demonstration of normal axillary lymph nodes: a learning curve. J Ultrasound Med. 1995;14:823–827
  21. Yang WT, Ahuja A, Tang A, Suen M, King W, Metreweli C. High resolution sonographic detection of axillary lymph node metastases in breast cancer. J Ultrasound Med. 1996;16:241–246
  22. Maurer J, William C, Steinkamp HJ, Knollmann FD, Felix R. Keratinization and necrosis: morphologic aspects of lymphatic metastases in ultrasound. Invest Radiol. 1996;31(9):545–549
  23. Vaidya JS, Vyas JJ, Thakur MH, Khandelwal KC, Mittra I. Role of ultrasonography to detect axillary node involvement in operable breast cancer. Eur J Surg Oncol. 1996;22:140–143
  24. Verbanck J, Vandewiele I, DeWinter H, Tytgat J, Van Aelst F, Tanghe W. Value of axillary ultrasonography and sonographically guided puncture of axillary nodes: a prospective study in 144 consecutive patients. J Clin Ultrasound. 1997;25(2):53–56
  25. Toriyabe Y, Nishimura T, Kita S, Saito Y, Miyokawa N. Differentiation between benign and metastatic cervical lymph nodes with ultrasound. Clin Radiol. 1997;52:927–932
  26. Cosgrove DO, Kedar RP, Bamber JC, Al-Murrani B, Davey JB, Fisher C, et al. Breast diseases: Colour Doppler US in differential diagnosis. Radiology. 1993;189:99–104
  27. Milz P, Lienemann A, Kessler M, Reiser M. Evaluation of breast lesions by power Doppler sonography. Eur Radiol. 2001;11:547–554
  28. Kook SH, Park HW, Lee YR, Lee YU, Pae WK, Park YL. Evaluation of solid breast lesions with power Doppler sonography. J Clin Ultrasound. 1999;27(5):231–237
  29. Rubin JM, Bude RO, Carson PL, Bree RL, Adler RS. Power Doppler US: a potentially useful alternative to Mean Frequency-based Colour Doppler US. Radiology. 1994;190:853–856
  30. Macsweeney JE, Cosgrove DO, Arenson J. Colour Doppler energy (power) mode ultrasound. Clin Radiol. 1996;51:387–390
  31. Bude RO, Rubin JM. Power Doppler sonography. Radiology. 1996;200:21–23
  32. Steinkamp HJ, Maurer J, Cornehl M, Knobber D, Hettwer H, Felix R. Recurrent cervical lymphadenopathy: differential diagnosis with colour duplex sonography. Eur Arch Otorhinolaryngol. 1994;251:404–409
  33. Ahuja AT, Ho SS, Leung SF, Kew J, Metreweli C. Metastatic adenopathy from nasopharyngeal carcinoma: successful response to radiation therapy assessed by colour duplex sonography. Am J Neuroradiol. 1999;20:151–156
  34. Chang DB, Yuan A, Yu CJ, Luh KT, Kuo SH, Yang PC. Differentiation of benign and malignant cervical lymph nodes with colour Doppler sonography. AJR Am J Roentgenol. 1994;162:965–968
  35. Choi MY, Lee JW, Jang KJ. Distinction between benign and malignant causes of cervical, axillary and inguinal lymphadenopathy: value of Doppler spectral waveform analysis. AJR Am J Roentgenol. 1995;165:981–984
  36. Na DG, Lim HK, Byun HS, Kim HD, Ko YH, Baek JH. Differential diagnosis of cervical lymphadenopathy: usefulness of colour Doppler sonography. AJR Am J Roentgenol. 1997;168:1311–1316
  37. Wu CH, Chang YL, Hsu WC, Ko JY, Sheen TS, Hsieh FJ. Usefulness of Doppler spectral analysis and power Doppler sonography in the differentiation of cervical lymphadenopathies. AJR Am J Roentgenol. 1998;171:503–509
  38. Ho SS, Metreweli C, Ahuja AT. Does anybody know how we should measure Doppler parameters in lymph nodes?. Clin Radiol. 2001;56:124–126
  39. Yang WT, Chang J, Metreweli C. Patients with breast cancer: differences in colour Doppler flow and gray-scale US features of benign and malignant axillary lymph nodes. Radiology. 2000;215:568–573
  40. Walsh JS, Dixon JM, Chetty U, Paterson D. Colour Doppler studies of axillary node metastases in breast cancer. Clin Radiol. 1994;49:192–194
  41. Hall JG. Functional anatomy of lymph nodes. In:  Stansfeld AG,  D'ardenne AJ editor. Lymph node biopsy interpretation. New York: Churchill Livingstone; 1992;p. 1–25
  42. Krishnamurthy S, Sneige N, Bedi DG, Edieken BS, Fornage BD, Kuerer HM, et al. Role of ultrasound-guided fine-needle aspiration of indeterminate and suspicious axillary lymph nodes in the initial staging of breast carcinoma. Cancer. 2002;95(5):982–988
  43. Hayashi M, Sakamoto G, Akiyama F, Kasumi F, Hatakeyama K. 23rd Annual San Antonio Breast Cancer Symposium, San Antonio, Texas, 6–9 December 2000. Morphological characteristics of metastatic nodes are important as a new prognostic indicator (Poster).

PII: S1078-8174(05)00054-4

doi: 10.1016/j.radi.2005.04.001

Radiography
Volume 12, Issue 2 , Pages 96-104 , May 2006